Imidazoline Antihypertensive Drugs: Selective I1-Imidazoline Receptors Activation
نویسندگان
چکیده
منابع مشابه
LNP 906, the first high-affinity photoaffinity ligand selective for I1 imidazoline receptors.
1 The hypotensive effect of imidazoline-like drugs, such as clonidine, was attributed both to alpha2-adrenergic receptors and nonadrenergic imidazoline receptors, which are divided into I1, I2 and I3 subtypes. 2 We have recently synthesized a derivative of (2-(2-chloro-4-iodo-phenylamino)-5-methyl-pyrroline (LNP 911), the first high-affinity and selective ligand for I1 receptors (I1R), with a p...
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ژورنال
عنوان ژورنال: Cardiovascular Therapeutics
سال: 2011
ISSN: 1755-5914
DOI: 10.1111/j.1755-5922.2011.00269.x